卡路里限制与寿命的之间关联的分子机制
Posted in 日记 on Sep 26th, 2007 No Comments »
Nutrient-Sensitive Mitochondrial NAD+ Levels Dictate Cell Survival
http://www.cell.com/content/article/abstract?uid=PIIS0092867407009737
Abstract:
A major cause of cell death caused by genotoxic stress is thought to be due tothe depletion of NAD+ from the nucleus and the cytoplasm. Here we show that NAD+ levels in mitochondria remain at physiological levels following genotoxic stress and can maintain cell viability even when nuclear and […]
